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The first hypothesis better fertility in heifers that had CL
2021-10-20
The first hypothesis, better fertility in heifers that had CL at day 0, was clearly supported by our results. Heifers with a CL had over 60% P/AI compared to ∼50% in heifers without CL. These results are consistent with several other studies reporting that cycling heifers have greater fertility than
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br Acknowledgements Support provided by projects PTDC SAU MI
2021-10-20
Acknowledgements Support provided by projects PTDC/SAU-MIC/115178/2009 and PEst-OE/QUI/UI0612/2011 from the Fundação para a Ciência e a Tecnologia, Portugal. Diabetes Mellitus Diabetes mellitus is a chronic, multisystem metabolic disorder caused by a combination of environmental and genetic f
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Here we studied the effects of BZ flurazepam
2021-10-20
Here we studied the effects of BZ flurazepam (FZ) at high doses in acute and chronic settings of tolerance and dependence in GluR-A−/− mice (Zamanillo et al., 1999). We used measurements in which the phenomenon of “learning while intoxicated” should play only a minor role in order to find out the si
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Gastric inhibitory polypeptide a hormone belonging to the
2021-10-19
Gastric inhibitory polypeptide, a hormone belonging to the glucagon-secretin family of peptides, exhibits protection against the neurodegeneration and also stimulates neurogenesis in adult rats in a paracrine manner (Gault and Holscher, 2008, Nyberg et al., 2005, Usdin et al., 1993). The expression
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We have previously shown in the same time
2021-10-19
We have previously shown in the same time frame reported here (10 min) that AG was not degraded into DAG [29] and that the half-life of AG in human serum is ∼10 min [49]. However, we cannot rule out in this study that there is not breakdown to DAG that could contribute to the levels of 125I-ghrelin
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Moreover the ubiquitous expression of the OTR
2021-10-19
Moreover, the ubiquitous D-Pantothenic acid of the OTR and GHSR was also observed in hippocampal and hypothalamic primary culture, indicating that this expression pattern is likely due to basal activity of these receptors. GPCR trafficking under control conditions has been linked to biased signalli
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br GSMs Secretase cleavage of APP
2021-10-19
GSMs γ-Secretase cleavage of APP generates a number of Aβ peptides [32], [137]. In most cells Aβ1–37, 38, 39, and 42 are produced at low levels (typically each represents 5–20% of total Aβ detected) and the major species generated is Aβ1–40 (typically over 50% of total Aβ). Other Aβ peptides can
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PP121 As shown in Table the results
2021-10-19
As shown in Table 3, the results of individual prediction modeling with chemicals at 0.4 mM, 0.6 mM, and 0.8 mM would lead to lesser sensitivity of 60.0%, 65.0%, and 65.0%, respectively, in microsome-unused group, and 85.0%, 85.0%, and 90.0%, in microsome-used group. If we consider only the results
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br PEPCK This enzyme decarboxylates and then
2021-10-19
PEPCK This enzyme decarboxylates and then phosphorylates oxaloacetate to form phosphoenolpyruvate (PEP) in the second step of gluconeogenesis after the carboxylation of pyruvate catalyzed by PC. PEPCK1 (PEPCK-C, encoded by the PCK1 gene) and PEPCK2 (PEPCK-M, encoded by the PCK2 gene) are two isof
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At the molecular level AZ
2021-10-19
At the molecular level AZ scaffold proteins including piccolo and bassoon have been shown to directly or indirectly associate with endocytic and actin-binding proteins such as ABP1 (Fenster et al., 2003), profilin, and GIT (Podufall et al., 2014) (Fig. 2B). ABP1 and profilin, via regulating F-actin,
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The observed tendency for higher plasma lactate levels in
2021-10-19
The observed tendency for higher plasma lactate levels in the aerated thermal exposure suggests increased reliance on lidocane metabolism to maintain function. This finding is supported by a recent study that observed an increased ṀO2 in European perch (Perca fluviatilis) exposed to a hyperoxic rat
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In HO OE group Barnesiella Eubacterium Parvibacter and
2021-10-19
In HO-1OE group, Barnesiella, Eubacterium, Parvibacter and were notably enriched in the gut. Barnesiella, belonging to Porphyromonadaceae, is able to utilize fucosyllactose as apexbt source to maintain bacterial cultures (Weiss et al., 2014). The enrichment of this microbial genus was consistent wit
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Signaling pathways that control the redox stress response in
2021-10-19
Signaling pathways that control the redox stress response in P. brasiliensis are poorly known, but in other dimorphic fungi, the involvement of MAPK is an important factor in this process [[13], [14], [15]]. For example, when alveolar macrophages are challenged with Aspergillus or Cryptococcus conid
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It was reported that GPR
2021-10-19
It was reported that GPR120 is expressed on macrophages in adipose tissue (Oh et al., 2010). Whether GPR120-positive rxr receptor in human and rat pancreas belongs to macrophages was studied. CD68 is a transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages (Ho
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Consistent with other studies on the metabolic effects of
2021-10-19
Consistent with other studies on the metabolic effects of an OM3 enriched diet [26,104,105], irrespective of gender, the lowest glucose levels were seen in the Bob-Cat groups fed OM3 diet. Sexual dimorphism was observed in insulin levels. The highest average levels were in the HFD fed [Tg(CAT)±] mal
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