• br Introduction Fatal drug overdoses have reached

  2018-11-05

  

  Introduction Fatal drug overdoses have reached epidemic levels in the United States, increasing 137% from 2000–2014 (Rudd, Aleshire, Zibbell, & Gladden, 2016). Growth in poisoning deaths, around 90% of which are now caused by drugs (Warner, Chen, Makuc, Anderson, & Miniño, 2011), were the most im

• It is observed from Tables that the o

  2018-11-05

  

  It is observed from Tables 1–6 that, the εo, ε∞, τ, and geff values of alcohols with amides mixtures (10%, 20%, 30%, 40%, 50%, 60%, 70%, 80% and 90%) lie between the individual values of pure alcohol and amides. This result indicates the existence of molecular association between the alcohol and ami

• br Funding Sources This work was supported by

  2018-11-05

  

  Funding Sources This work was supported by an Applied Research Support Fund Award from the NYU Office of Industrial Liaison, center of excellence funding from NYU School of Medicine to the Dept of Urology, and a translational pilot project award from the NYU Cancer Institute center grant from NIH

• br Diabetic retinopathy and age

  2018-11-05

  

  Diabetic retinopathy and age-related macular degeneration are leading causes of blindness among older adults. Both conditions are more prevalent among those with chronic kidney disease (CKD). However, few if any previous examinations of CKD and visual impairment (VI) have been conducted. This gap

• In a single study using a

  2018-11-05

  

  In a single study using a murine knockout model, significant reductions both in litter size and fetal weight in ANXA5-null mice (ANXA5-KO) was reported (Ueki et al., 2012), if accepted this suggests that maternal expression of ANXA5 in the circulation may be crucial for maintaining normal pregnancy;

• The following are the supplementary data related to this

  2018-11-05

  

  The following are the supplementary data related to this article. Funding Sources This work is funded by the Medical Research Council (H8RSRS00), Ovarian Cancer Action (HER00070), the Oxford Biomedical Research Centre, the National Institute for Health Research (HJRWAC05) and the Experimental Ca

• HLA transgenic mice are widely used to model

  2018-11-05

  

  HLA-transgenic mice are widely used to model the human T cell response in mice. We focused the present study on the HLA B*0702 allele, which is associated with strong T cell response in terms of magnitude and breath (Weiskopf et al., 2013), thereby allowing us to test the role of multiple cross-reac

• br Materials and Methods br Results br Discussion

  2018-11-05

  

  Materials and Methods Results Discussion We report that increased GRK2 levels and functionality in either luminal or basal cancer acetylcholinesterase inhibitor can drive the acquisition and maintenance of tumoral proliferation and survival. Elevated GRK2 protein levels are detected in dif

• In vitro studies using shRNAs

  2018-11-05

  

  In vitro studies using shRNAs to target >100 autophagy regulators identified a number of breast cancer cell lines that are dependent upon functional autophagy for growth even in the absence of stress (Maycotte et al., 2014). Importantly however, some tumor cell lines were barely affected by autophag

• In summary it is clear that the

  2018-11-05

  

  In summary, it is clear that the Late Cretaceous is a major episode of magmatic activities and the related large scale Sn–W mineralization distribute throughout the southeast Yunnan and northeast Vietnam. Combining the new data of this study and published igneous rocks and mineralization ages (Appen

• Sleep is an important modulator of hormonal release

  2018-11-05

  

  Sleep is an important modulator of hormonal release, glucose regulation and cardiovascular function. In particular slow-wave sleep, the most restorative sleep stage, is associated with decreased heart rate, blood pressure, sympathetic nervous activity and cerebral glucose utilization, compared with

• br Materials and methods br Results

  2018-11-05

  

  Materials and methods Results Discussion In SPR studies, the binding of vancomycin to the control surfaces was much weaker than that to doc-KAA surfaces, consistent with previous observations that vancomycin specifically binds to the bacterial cell wall precursor lipid II, rather than to ph

• br Acknowledgments This research was

  2018-11-05

  

  Acknowledgments This research was sponsored by the U.S. Naval Research Laboratory (WU# 69-6595). Participation of E. Archibong was through an ASEE sponsored internship. A. Gleaves and S. Monk were supported through a National Science Foundation (NSF) and Office of Naval Research (ONR) sponsored s

• br Introducci n El objetivo de este

  2018-11-05

  

  Introducción El objetivo de este artículo consiste en contribuir a una reinterpretación del papel que desempeña el Estado en el funcionamiento de la actividad económica, en especial en las coyunturas económicas, de acuerdo con el enfoque de la demanda efectiva. Con este fin se utiliza una metodol

• Asymptomatic colonization of the nasopharynx almost invariab

  2018-11-03

  

  Asymptomatic colonization of the nasopharynx almost invariably precedes disease; however, pneumococci vary in their capacity to colonize the nasopharynx, both in humans and in animal models. Certain serotypes and/or clonal groups are more often isolated from carriers, while others are more often iso

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