• In a single study using a

  2018-11-05

  

  In a single study using a murine knockout model, significant reductions both in litter size and fetal weight in ANXA5-null mice (ANXA5-KO) was reported (Ueki et al., 2012), if accepted this suggests that maternal expression of ANXA5 in the circulation may be crucial for maintaining normal pregnancy;

• The following are the supplementary data related to this

  2018-11-05

  

  The following are the supplementary data related to this article. Funding Sources This work is funded by the Medical Research Council (H8RSRS00), Ovarian Cancer Action (HER00070), the Oxford Biomedical Research Centre, the National Institute for Health Research (HJRWAC05) and the Experimental Ca

• HLA transgenic mice are widely used to model

  2018-11-05

  

  HLA-transgenic mice are widely used to model the human T cell response in mice. We focused the present study on the HLA B*0702 allele, which is associated with strong T cell response in terms of magnitude and breath (Weiskopf et al., 2013), thereby allowing us to test the role of multiple cross-reac

• br Materials and Methods br Results br Discussion

  2018-11-05

  

  Materials and Methods Results Discussion We report that increased GRK2 levels and functionality in either luminal or basal cancer acetylcholinesterase inhibitor can drive the acquisition and maintenance of tumoral proliferation and survival. Elevated GRK2 protein levels are detected in dif

• In vitro studies using shRNAs

  2018-11-05

  

  In vitro studies using shRNAs to target >100 autophagy regulators identified a number of breast cancer cell lines that are dependent upon functional autophagy for growth even in the absence of stress (Maycotte et al., 2014). Importantly however, some tumor cell lines were barely affected by autophag

• In summary it is clear that the

  2018-11-05

  

  In summary, it is clear that the Late Cretaceous is a major episode of magmatic activities and the related large scale Sn–W mineralization distribute throughout the southeast Yunnan and northeast Vietnam. Combining the new data of this study and published igneous rocks and mineralization ages (Appen

• Sleep is an important modulator of hormonal release

  2018-11-05

  

  Sleep is an important modulator of hormonal release, glucose regulation and cardiovascular function. In particular slow-wave sleep, the most restorative sleep stage, is associated with decreased heart rate, blood pressure, sympathetic nervous activity and cerebral glucose utilization, compared with

• br Materials and methods br Results

  2018-11-05

  

  Materials and methods Results Discussion In SPR studies, the binding of vancomycin to the control surfaces was much weaker than that to doc-KAA surfaces, consistent with previous observations that vancomycin specifically binds to the bacterial cell wall precursor lipid II, rather than to ph

• br Acknowledgments This research was

  2018-11-05

  

  Acknowledgments This research was sponsored by the U.S. Naval Research Laboratory (WU# 69-6595). Participation of E. Archibong was through an ASEE sponsored internship. A. Gleaves and S. Monk were supported through a National Science Foundation (NSF) and Office of Naval Research (ONR) sponsored s

• br Introducci n El objetivo de este

  2018-11-05

  

  Introducción El objetivo de este artículo consiste en contribuir a una reinterpretación del papel que desempeña el Estado en el funcionamiento de la actividad económica, en especial en las coyunturas económicas, de acuerdo con el enfoque de la demanda efectiva. Con este fin se utiliza una metodol

• Asymptomatic colonization of the nasopharynx almost invariab

  2018-11-03

  

  Asymptomatic colonization of the nasopharynx almost invariably precedes disease; however, pneumococci vary in their capacity to colonize the nasopharynx, both in humans and in animal models. Certain serotypes and/or clonal groups are more often isolated from carriers, while others are more often iso

• M hominis is not stainable by Gram stain and

  2018-11-03

  

  M. hominis is not stainable by Gram stain and recognition of its pinpoint-sized colonies requires experienced laboratory personnel. BacT/ALERT and BACTEC media (used for blood cultures) contain sodium polyanethol sulfonate, which may inhibit Mycoplasma growth (Waites and Canupp, 2001), and growth ma

• In parallel with drug monitoring disease monitoring through

  2018-11-03

  

  In parallel with drug monitoring, disease monitoring through non-invasive biomarkers plays an important role in IBD patients, as it allows an assessment of the inflammatory burden without the risks involved in colonoscopy-related procedures. Calprotectin constitutes up to 60% of the cytosolic protei

• br Data This data article includes the N

  2018-11-03

  

  Data This data article includes the N- and O-glycome of MKN45 cells and assesses the glycosylation alterations induced by ST3GAL4 overexpression. In addition, we provide the data on the proteins with significant increased sialylated N-glycans upon ST3GAL4 overexpression. Experimental design, m

• br Methods br Results br Discussion This study looked

  2018-11-03

  

  Methods Results Discussion This study looked at cortical thickness estimates at three independent time points (ages 18, 19, and 21, respectively) in adolescent marijuana and alcohol users compared to controls with limited substance use histories. We found significant between-group differenc

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