• In this issue of EBioMedicine Zhang et al study

  2018-11-13

  

  In this issue of EBioMedicine, Zhang et al. study the effect of weight loss on the gut microbiota and metabolism of severely obese children (). About half of these children had “simple obesity” (SO) without underlying pathology, while the other group had been diagnosed with Prader–Willi Syndrome (PW

• Although it is currently unclear if DNA methylation changes

  2018-11-13

  

  Although it is currently unclear if DNA methylation changes are the cause or the consequence of the disease, it is clear that DNA methylation changes occur early during disease pathogenesis and precede disease detection by histological and/or imaging methods. Several DNA methylation-based biomarkers

• Cost effectiveness of varicella vaccination might be affecte

  2018-11-13

  

  Cost-effectiveness of varicella vaccination might be affected by several interacting factors. First, reducing VZV circulation by varicella vaccination might result in an increase in HZ incidence (Schuette and Hethcote, 1999; Brisson et al., 2000; Gidding et al., 2005; Karhunen et al., 2010) and an a

• A concern for many potential inhibitors of restenosis is

  2018-11-13

  

  A concern for many potential inhibitors of restenosis is that their anti-proliferative effects are not specific to SMC and can therefore also inhibit proliferation of endothelial cells (EC) that line the lumen. Delayed re-endothelialization of the treated area creates a thrombogenic surface for plat

• The protocol for blood specimen procurement was approved by

  2018-11-13

  

  The protocol for blood specimen procurement was approved by the Institutional Review Board of Thomas Jefferson University. Seventeen UM patients, including ten patients who had liver only metastasis and seven patients who had hepatic and extra-hepatic metastases, were enrolled in this study between

• A likely scenario for the

  2018-11-13

  

  A likely scenario for the immediate future in the HIV vaccine field will be the development of an HIV vaccine with proven efficacy against a specific clade. One of the critical questions that emerges from this is whether to support the immediate introduction of a clade matched vaccine in regions whe

• Of KIT mutations seven occurred in exon five in exon

  2018-11-12

  

  Of 15 KIT mutations, seven occurred in KU-60019 manufacturer 11, five in exon 13, three in exon 17, and none in exon 18 (Table 2). The most common mutation was L576P (n = 6) and K642E (n = 6), followed by D820Y (n = 2), and finally Y559D (n = 1), L657F (n = 1), and G827R (n = 1). Although only thre

• It was reported that the microstructure in HAZ TMAZ

  2018-11-12

  

  It was reported that the microstructure in HAZ, TMAZ and WN vary particularly in rgs protein hardenable aluminium alloys like 7xxx series [7]. The variation in microstructure leads to the variation in hardness and corrosion resistance of AA7075 aluminium weld. The softening of HAZ is one of the reas

• The investigation of metal particles nanometer sized

  2018-11-12

  

  The investigation of metal particles (nanometer sized) is important for various applications in blast enhanced explosives, particles in high performance ceramics and rocket propellants and pyrotechnics. Methods of thermal analysis are often applied to investigate the controlled compositions of metal

• Although there is an increase in clinical

  2018-11-12

  

  Although there is an increase in clinical use of zirconia ceramics due to improved mechanical properties, further evidence regarding the adhesive cementation of Y-TZP restorations is necessary for the clinical success and the long-term performance of such restorations through establishing the most r

• Befort and Hattrup suggested that the

  2018-11-12

  

  Befort and Hattrup (2003) suggested that Before the Internet the job performance is significantly affected by the job demands as well as organizational goals and objectives. Individuals who are highly emotional intelligent are able to regulate their emotions more effectively by maintaining a positi

• In view of the benefits highlighted

  2018-11-12

  

  In view of the benefits highlighted in the preceding paragraph, BPE has continued to receive enormous research attention, especially in the developed countries as Meir et al. (2009) indicated. However, the existing studies on BPE focus more on office than residential buildings (see Gossauer, 2005; M

• The organizing principles of space signify

  2018-11-12

  

  The organizing principles of space signify interpersonal relationships as much as they indicate the general state of mankind (Tuan, 1977). Therefore, lifestyle highly depends on one׳s ownership of a private space (Rossler et al., 2005; Hanson, 2008). In addition, the needs and abilities of residents

• br Case reports br Discussion MFH is a pleomorphic

  2018-11-12

  

  Case reports Discussion MFH is a pleomorphic sarcoma common among adults between 60 and 70 years of age. It has been determined to exhibit high-grade and biological aggressiveness. MFH typically occurs in the extremities and the retroperitoneum, predominantly in men. In our study, the ratio of

• Introduction The unpredictability of hypertrophic scars HTSs

  2018-11-12

  

  Introduction The unpredictability of hypertrophic scars (HTSs) and keloids can confuse the most experienced physicians. In 2014, the International Advisory Panel on scar management published a revision of the recommended practices promoted by the first advisory panel in 2002, resulting in new treat

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