• br Results Compared to the respective untreated

  2019-04-20

  

  Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB

• nmda receptor antagonist Article of the Universal Declaratio

  2019-04-20

  

  Article 25 of the Universal Declaration of Human Rights states that “everyone has the right to a standard of living adequate for the health and well-being of himself and of his family, including food, clothing, housing and medical care and necessary social services, and the right to security in the

• El problema del populismo ocup de manera

  2019-04-20

  

  El problema del populismo ocupó de manera temprana la obra de Ernesto Laclau. Su primera obra, publicada en 1977 como Politics and ideology in marxist theory. Capitalism, fascism, populism, incluye el capítulo “Hacia una teoría del populismo”. La preocupación por el asunto no es meramente teórica si

• br Cholera remains a serious global public health problem

  2019-04-20

  

  Cholera remains a serious global public health problem, disproportionately affecting poor individuals, causing illness and death for thousands of people each year. Cholera cases are on the rise, with 47% more cases reported to WHO in 2014 than in 2013. Innovative approaches to control the disease

• onde introduzimos a negritude como uma concep o adotada

  2019-04-19

  

  É onde introduzimos order Sulindac sulfide negritude como uma concepção adotada pelos intelectuais e movimentos sociais ligados à causa negra no Brasil. A negritude foi conceituada por seu criador, o poeta e intelectual Aimé Cesairé, como “o simples reconhecimento do fato de ser negro, a aceitação d

• The deletion of q seen in our patient

  2019-04-19

  

  The deletion of 14q seen in our patient included the IGH locus at 14q32.33. This is noteworthy, because loss of 14q has been reported as a recurrent aberration acquired during the natural history of CLL. The acquisition of a del(14) may thus be indicative of CLL in transformation. In a study of a la

• br Conclusion br Authors contribution br Competing interests

  2019-04-19

  

  Conclusion Authors’ contribution Competing interests Acknowledgments Case report Imatinib has radically changed prognosis in chronic-phase Chronic Myeloid Leukemia (CML), with 90% overall survival rate at 8yrs, and 40–70% of patients achieving a stable MMR [1]. Even better results hav

• br Prognosis The management of AML in

  2019-04-19

  

  Prognosis The management of AML in the elderly patient presents a significant challenge for hematologists. Careful evaluation of both patient and disease is required in each individual case to make optimal management decisions, and maximize the benefit to the patient. Apart from the extremely old

• br Materials and methods The study was

  2019-04-19

  

  Materials and methods The study was designed as an open label, single institution phase I study at the National Heart, Lung, Blood Institute, National Institutes of Health and was approved by Institutional Review Board (NCT01629082). All patients signed an informed consent prior to enrollment and

• Although high and variable frequencies of sickle cell trait

  2019-04-19

  

  Although high and variable frequencies of sickle cell trait in different ethnic groups in Uganda have been reported previously, those data were from around 70 years ago and were based on small sample sizes. Thus, the findings of Ndeezi and colleagues provide a contemporary overview that is nationall

• There are some models of sleep deprivation

  2019-04-19

  

  There are some models of sleep deprivation, such as acute or chronic, total or selective sleep deprivation, sleep restriction, or sleep fragmentation. Modifed multiple platform method (MMPM) in our study causes a particularly strong reduction in REM sleep, breaks the sleep continuity. Previous studi

• These studies demonstrated that the levels

  2019-04-19

  

  These studies demonstrated that the levels of essential Puromycin in healthy pregnant women were significantly different from those of the general population. There is a need to evaluate more pregnant women, especially from different races, for the purpose of establishing specific normative levels o

• br Conclusions br Conflict of interest br Acknowledgments Th

  2019-04-19

  

  Conclusions Conflict of interest Acknowledgments This study was based in part on data from the National Health Insurance Research Database provided by the Bureau of National Health Insurance, Department of Health and managed by the National Health Research Institutes (registration number 10

• Since many decades bone tumours have stimulated imagination

  2019-04-19

  

  Since many decades, bone tumours have stimulated imagination of researchers and numerous therapeutic alternatives have been proposed [134,135, Fig. 4]. The better knowledge of OPG/RANK/RANKL system leads to the development of peptides mimicking OPG and blocking RANK–RANKL interactions [136–139]. Inh

• br Materials and methods br Results br Discussion

  2019-04-19

  

  Materials and methods Results Discussion Utilizing IHC, the majority of OS samples were positive for RANKL (68%), with RANKL staining detectable in OS tumor mmp inhibitor and tumor anaplastic cells. However, a wide range of RANKL expression within the OS component was observed and many sam

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