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Previous studies demonstrate that chiral biointerface has
2023-04-06
Previous studies demonstrate that chiral biointerface has great influence on cells adhesion and proteins adsorption [39], [40], [41], [42], [43], which inspired us to further develop antimicrobial materials or surfaces by taking advantage of the “chiral taste” of microbes. L-borneol is a hydrophobic
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Introduction Antimicrobial resistance is a
2023-04-06
Introduction Antimicrobial resistance is a growing health threat worldwide that has been associated with incorrect prescription and overuse of Flutamide [1]. Considering that physicians play a central role in antibiotic usage, a better understanding of their prescribing behaviours and their knowle
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AR Vs are truncated AR proteins lacking the AR ligand
2023-04-06
AR-Vs are truncated AR proteins lacking the AR ligand-binding domain (AR-LBD) [6]. While AR-Vs have frequently been detected in CRPC, their expression and functional role in benign prostate tissues and primary prostate cancers is not readily apparent. Structural rearrangements in the AR gene and alt
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Fig shows a possible scheme of the generation of AP
2023-04-06
Fig. 8 shows a possible scheme of the generation of AP(+)-exosomes based on this study. In response to inflammatory stimuli, ERAP1 is secreted from ER into the extracellular milieu through the conventional secretion pathway. On the other hand, exosomes are derived from the endosomal pathway, and are
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Rising depolarization was observed during and decaying depol
2023-04-06
Rising depolarization was observed during and decaying depolarization after the photostimulation (Fig. 1D). The slow decrease of the firing rate after photostimulation is also a remarkable characteristic of the striatal neuron (Figs. 1E, 2 and 3), since the cortex pyramidal neurons (data not shown)
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It could be hypothesized that the adiponectin system is regu
2023-04-06
It could be hypothesized that the adiponectin system is regulated by gonadal steroid hormones. The lowest concentrations of adiponectin, AdipoR1 and AdipoR2 proteins in the endometrium and myometrium during the mid-luteal and late-luteal phases suggest that progesterone suppresses the expression of
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br Materials and methods br Results
2023-04-06
Materials and methods Results Discussions Diabetes is mainly divided into Type 1 diabetes and Type 2 diabetes [16]. Type 2 diabetes, featured by insulin resistance, results from environmental factors and poor eating habits [2]. Type 2 diabetes accounts for more than 95% of the diabetic pati
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Since the introduction of zebrafish into the laboratory many
2023-04-06
Since the introduction of zebrafish into the laboratory, many milestones have been achieved that firmly establish this organism as a prominent genetic model for biology and medicine. Many features make this species an organism of easy maintenance in laboratory which provides advantages to understand
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Introduction br This paper is a
2023-04-06
Introduction This paper is a commentary on the history of language among the Aché. What was language for the Aché prior to contact with Paraguayan society? How has the Aché language come to be endangered? Why is language such an important issue today? In exploring these questions I come to a slig
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Fmoc-D-Phe(4-Cl)-OH br Material and methods br Results br Di
2023-04-06
Material and methods Results Discussion Clinical gene therapy trials with viral vectors have been in use for treatment of various genetic disorders and diseases, however efficacious, targetable and highly reliable non-viral delivery systems are needed for safe and long-term applications. De
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The identification of novel kinase inhibitor scaffolds is hi
2023-04-06
The identification of novel kinase inhibitor scaffolds is highly desirable in order to develop selective kinase inhibitors. Small-molecule inhibitors of Interleukin-2-inducible T-cell kinase (Itk) that are based on the 3-aminopyridin-2-one fragment 1 have been reported. Despite derivatisation of 1 y
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Evidences have suggested that impairment of CK
2023-04-06
Evidences have suggested that impairment of CK activity contributes to inhibition of Na+, K+-ATPase and H+-ATPase activities during infectious diseases, since these ATPases are dependent of ATP, as observed by Baldissera et al. [31] in fish experimentally infected by Aeromonas caviae. We observed t
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br The role of LOX plays
2023-04-06
The role of 12/15-LOX plays in autophagy Autophagy is a process by which cellular material is delivered to lysosomal to degrade the damaged organelles and proteins to facilitate nutrient recycling (Towers and Thorburn, 2016). There has been characterized three types of autophagy-macroautophagy, m
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br Materials and methods br Results
2023-04-03
Materials and methods Results Discussion Japanese encephalitis caused by JEV is characterized by 680C91 mg neuron death. However, the underlying mechanism is not fully understood. We and other researchers have demonstrated that JEV induces apoptosis by ER stress-mediated IRE1/JNK and ROS-me
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A strain previously reported as demonstrating
2023-04-03
A strain previously reported as demonstrating strong antifungal activity and suitability for food applications is Lactobacillus reuteri R29 (Axel et al., 2016, Oliveira et al., 2015). Oliveira et al. (2015) demonstrated that the cell-free supernatant (cfs) of medium fermented for 48 h with this stra
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